Invention Grant
- Patent Title: Method for reduction of interferences in immunoassays
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Application No.: US15995572Application Date: 2018-06-01
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Publication No.: US11320423B2Publication Date: 2022-05-03
- Inventor: Barbara Upmeier , Toralf Zarnt , Dieter Roessler , Johannes Polz
- Applicant: Roche Diagnostics Operations, Inc.
- Applicant Address: US IN Indianapolis
- Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee Address: US IN Indianapolis
- Agency: Stinson LLP
- Priority: EP15197192 20151201
- Main IPC: G01N31/00
- IPC: G01N31/00 ; G01N33/53 ; G01N33/541 ; G01N33/543 ; G01N21/64 ; G01N21/78 ; G01N33/531 ; G01N33/538 ; G01N33/569 ; G01N33/576

Abstract:
Disclosed is an immunoassay method for detecting an analyte such as an antigen or an antibody in an isolated sample suspected to contain the analyte by incubating the sample with a plurality of binding partners, one of which carries a detectable label, wherein a label-specific binding partner is added that does not carry a label but binds to the detectable label. The method is applicable for a large variety of analytes and has proven particularly useful for analyte antibodies of the IgG and IgM class present in samples due to infections by pathogens. Also disclosed is a reagent kit useful for the method comprising at least two analyte-specific binding partners one of which carries a detectable label and a label-specific binding partner that binds to said detectable label but itself does not carry a detectable label.
Public/Granted literature
- US20180348211A1 METHOD FOR REDUCTION OF INTERFERENCES IN IMMUNOASSAYS Public/Granted day:2018-12-06
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