Techniques regarding personalizing one or more design layouts of a user interface for application software are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a design component that can generate a design layout of a user interface for application software by adjusting an initial design layout of the user interface based on interactions via the user interface and a design perturbation preference associated with the initial design layout.