A currency bill processing device for counting, denominating, discriminating, and/or sorting the currency bills and subsequently disinfecting the currency bills without any manual intervention. The currency bill processing device can process the currency bills at a speed of up to 1000 bills per minute. The currency bill processing device includes one or more elongated UV-C LED strips mounted on a rigid aluminum or copper base which can be mounted on an outer or exposed side of a support plate or reject receptacle plate or stacker guide bar plate located at the end of the currency bill conveying path. A disinfection unit of the currency bill processing device including the elongated UV-C LED strip that can activate and deactivate with turning-on and -off of the currency bill conveying mechanism respectively.