The present application discloses a protection circuit for a memory in a display panel and a display panel. The circuit comprises a timing controller, a memory, a power circuit, and a switching circuit. Instead of having a computer provide a write protection signal to the memory to limit data in the memory from being overwritten, the power circuit provides a stable and reliable write protection signal to the memory, and then the timing controller controls the switching circuit to be turned on for grounding the write protection signal of the memory only when an instruction to write data to the memory is received.