Described herein are examples of illustrative orthopedic staples, systems and methods. In an illustrative orthopedic staple for fusion of a foot or ankle bone fracture, the staple includes a bridge, a first staple leg and a second staple legs. The bridge of the illustrative staple extends from a first end portion to a second end portion along a first direction. The bridge also includes a step down region located between the first end portion and the second end portion, the step down region having a height along the insertion axis of the staple. In some examples, the first staple leg has a first staple leg height extending from the bridge to the first distal tip and the second staple leg has a second staple leg height extending from the bridge to the second distal tip, and the first staple leg height is greater than the second staple leg height.