Invention Grant
- Patent Title: Muscarinic agonists
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Application No.: US16728762Application Date: 2019-12-27
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Publication No.: US11324738B2Publication Date: 2022-05-10
- Inventor: Giles Albert Brown , Miles Stuart Congreve , Mark Pickworth , Mark David Rackham , Benjamin Gerald Tehan
- Applicant: Heptares Therapeutics Limited
- Applicant Address: GB Cambridge
- Assignee: Heptares Therapeutics Limited
- Current Assignee: Heptares Therapeutics Limited
- Current Assignee Address: GB Cambridge
- Agency: Fish & Richardson P.C.
- Priority: GB1513740 20150803
- Main IPC: A61P25/14
- IPC: A61P25/14 ; A61P25/28 ; C07D401/14 ; C07D413/14 ; A61K31/4523

Abstract:
This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1a or a salt thereof, wherein n, p, Q, R1, R2, R3, R9 and R4 are as defined herein.
Public/Granted literature
- US3140735A Horizontal bagging machine and lift Public/Granted day:1964-07-14
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