Invention Grant
- Patent Title: Methods of use and pharmaceutical combinations of histone deacetylase inhibitors and CD20 inhibitory antibodies
-
Application No.: US15670743Application Date: 2017-08-07
-
Publication No.: US11324744B2Publication Date: 2022-05-10
- Inventor: Simon Steward Jones , Chengyin Min , Steven Norman Quayle
- Applicant: Acetylon Pharmaceuticals Inc.
- Applicant Address: US MA Boston
- Assignee: Acetylon Pharmaceuticals Inc.
- Current Assignee: Acetylon Pharmaceuticals Inc.
- Current Assignee Address: US MA Boston
- Agency: Lathrop GPM LLP
- Agent Brian Trinque
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61K45/06 ; A61K39/395 ; A61P35/00 ; A61K9/00 ; C07K16/28 ; A61K39/00
Abstract:
The disclosure relates to pharmaceutical combinations comprising an HDAC6 selective inhibitor and a CD20 inhibitory antibody for the treatment of a B-cell disorder, such as cancer, in a subject in need thereof. Also provided herein are methods for treating a B-cell disorder in a subject in need thereof, comprising administering to the subject an effective amount of an HDAC6 selective inhibitor and a CD20 inhibitory antibody.
Public/Granted literature
Information query
