Invention Grant
- Patent Title: Method for producing peptide ACE inhibitors
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Application No.: US16221836Application Date: 2018-12-17
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Publication No.: US11324810B2Publication Date: 2022-05-10
- Inventor: Marco Santamaria
- Applicant: Marco Santamaria
- Applicant Address: US NM Albuquerque
- Assignee: Marco Santamaria
- Current Assignee: Marco Santamaria
- Current Assignee Address: US NM Albuquerque
- Agent Marco Henry Santamaria
- Main IPC: A61K38/55
- IPC: A61K38/55 ; A61K38/48 ; C12N9/48 ; C12N9/76 ; A61P9/12 ; A61K38/08 ; A23L29/00 ; C12N9/64

Abstract:
A method for producing ACE Inhibitor peptides from a protein source or plasma is disclosed. The method utilizes proteolysis by intestinal, blood-circulating, or membrane-bound proteases. The initial synthesis step could require obtaining a protein source either from a human or animal. A protease is added to either a given plasma protein or plasma and incubated. Following incubation, the protease activity must be quenched using a protease inhibitor to inactivate the protease. After incubation with protease inhibitor, the solution will contain a mixture of bioactive ACE inhibitory peptides and inert peptides. This mixture may be purified to select for the ACE inhibitory peptides through centrifugation. The mixture may also be sterilized to remove any microbial contaminants. The ACE inhibitory peptides can be mixed with protein powders, incorporated into baked good and put into other food products to provide food products with the added benefit of lowering blood pressure.
Public/Granted literature
- US20190262436A1 METHOD FOR PRODUCING PEPTIDE ACE INHIBITORS Public/Granted day:2019-08-29
Information query
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