Invention Grant
- Patent Title: Methods and compositions for activation of innate immune responses through RIG-I like receptor signaling
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Application No.: US16595288Application Date: 2019-10-07
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Publication No.: US11324817B2Publication Date: 2022-05-10
- Inventor: Michael J. Gale, Jr. , Gretja Schnell , Yueh-Ming Loo
- Applicant: University of Washington through its Center for Commercialization
- Applicant Address: US WA Seattle
- Assignee: University of Washington through its Center for Commercialization
- Current Assignee: University of Washington through its Center for Commercialization
- Current Assignee Address: US WA Seattle
- Agency: Christensen O'Connor Johnson Kindness PLLC
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K39/00 ; A61K39/39 ; C07H21/04 ; A61K45/06 ; C12N15/117 ; A61K31/00
Abstract:
Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome.
Public/Granted literature
- US20200276294A1 Methods and Compositions for Activation of Innate Immune Responses Through RIG-I Like Receptor Signaling Public/Granted day:2020-09-03
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