Invention Grant
- Patent Title: Modified virus-like particles of CMV
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Application No.: US16696161Application Date: 2019-11-26
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Publication No.: US11324836B2Publication Date: 2022-05-10
- Inventor: Martin Bachmann , Andris Zeltins , Paul Pumpens
- Applicant: SAIBA AG
- Applicant Address: CH Rämismühle
- Assignee: SAIBA AG
- Current Assignee: SAIBA AG
- Current Assignee Address: CH Rämismühle
- Agency: Medler Ferro Woodhouse & Mills PLLC
- Priority: EP14189897 20141022,EP15184192 20150908
- Main IPC: A61K47/64
- IPC: A61K47/64 ; A61K39/35 ; C07K14/005 ; A61K39/12 ; A61K39/08 ; A61K39/00 ; A61K39/015 ; A61K39/145 ; A61K39/155 ; A61K39/39 ; C07K14/33 ; C07K14/725 ; C12N7/00

Abstract:
The present invention relates to virus-like particles of plant virus Cucumber Mosaic Virus (CMV), and in particular to modified VLPs of CMV comprising Th cell epitopes, in particular universal Th cell epitopes. Furthermore, these modified VLPs serve as, preferably, vaccine platform, for generating immune responses, in particular antibody responses, against antigens linked to said modified VLPs. The presence of the Th cell epitopes, in particular universal Th cell epitopes, led to a further increase in the generated immune response.
Public/Granted literature
- US20200155699A1 MODIFIED VIRUS-LIKE PARTICLES OF CMV Public/Granted day:2020-05-21
Information query
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