A bi-directional perfusion cannula comprising a flexible elongated tube 1 for insertion into an artery having a first aperture 3 at a distal end and a second aperture 4 formed rearward of the first aperture, the elongated tube can be bent in correspondence of the second aperture to orient it in a direction opposite to the insertion direction. The cannula is provided with a tape 5 having a first end portion shaped as a ring, fixed on an outer surface of the elongated tube, and a second end portion opposite to the first end portion either coupled to or being integral with a belt 7 defining a strap 11 with holes 12 and at least a prong 13 integral with the strap and configured to engage a respective hole, wherein the belt is configured to be tightened around an outer surface of the artery.