Invention Grant
- Patent Title: Functionalized N,N-dialkylamino phenyl ethers and their method of use
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Application No.: US16764424Application Date: 2018-11-20
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Publication No.: US11325883B2Publication Date: 2022-05-10
- Inventor: Edward G. Melenski , Wayne E. Childers , Marlene A. Jacobson , Magid A. Abou-Gharbia
- Applicant: Temple University—Of The Commonwealth System of Higher Education
- Applicant Address: US PA Philadelphia
- Assignee: Temple University—Of The Commonwealth System of Higher Education
- Current Assignee: Temple University—Of The Commonwealth System of Higher Education
- Current Assignee Address: US PA Philadelphia
- Agency: Riverside Law LLP
- International Application: PCT/US2018/061911 WO 20181120
- International Announcement: WO2019/103989 WO 20190531
- Main IPC: C07C225/16
- IPC: C07C225/16 ; A61K31/138 ; A61P3/00 ; C07C49/255 ; A61P31/10

Abstract:
Pharmaceutical compositions of the invention comprise functionalized N,N-dialkylamino phenyl ethers derivatives having a disease-modifying action in the treatment of diseases associated with lysosomal storage dysfunction that include Gaucher's disease, and any disease or condition involving lysosomal storage dysfunction.
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