Invention Grant
- Patent Title: Small molecule inducers of autophagy
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Application No.: US17112980Application Date: 2020-12-04
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Publication No.: US11325898B2Publication Date: 2022-05-10
- Inventor: Jef De Brabander , Qiren Liang , Beth Levine , Wei-Chung Chiang
- Applicant: Board of Regents, The University of Texas System
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Richard Aron Osman
- Main IPC: C07D405/04
- IPC: C07D405/04 ; C07D405/14 ; C07D231/06 ; C07D403/04 ; C07D231/12 ; C07D401/04 ; C07D413/10 ; C07D413/04 ; C07D409/04 ; C07D405/06 ; C07D417/04 ; C07D405/12
Abstract:
Small molecule disruptors of Beclin-1/Bcl-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity.
Public/Granted literature
- US20210115024A1 Small molecule inducers of autophagy Public/Granted day:2021-04-22
Information query
