Invention Grant
- Patent Title: Method for manufacturing a stable emulsion for peptide delivery
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Application No.: US16477534Application Date: 2018-01-24
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Publication No.: US11325959B2Publication Date: 2022-05-10
- Inventor: Jean-Pascal Conduzorgues
- Applicant: OSE IMMUNOTHERAPEUTICS
- Applicant Address: FR Nantes
- Assignee: OSE IMMUNOTHERAPEUTICS
- Current Assignee: OSE IMMUNOTHERAPEUTICS
- Current Assignee Address: FR Nantes
- Agency: Saliwanchik, Lloyd & Eisenchenk
- Priority: EP17305079 20170125
- International Application: PCT/EP2018/051647 WO 20180124
- International Announcement: WO2018/138110 WO 20180802
- Main IPC: C07K14/00
- IPC: C07K14/00 ; C07K14/47 ; A61K9/107 ; A61K38/10 ; A61K38/17 ; A61K39/00

Abstract:
The present invention pertains to a method for manufacturing a ready-to-use peptide emulsion on the industrial scale, comprising the step of emulsifying a suspension of at least two peptides under low shear conditions with at least one adjuvant. It is also directed to a ready-to-use emulsion obtainable according to this method. This invention allows the delivery of a scalable emulsion of peptides which preserves their integrity and fulfills the requirements needed for a pharmaceutical sterile product.
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