Invention Grant
- Patent Title: Biparatopic and multiparatopic antibodies with common light chain and method of use
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Application No.: US16603711Application Date: 2018-04-09
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Publication No.: US11325982B2Publication Date: 2022-05-10
- Inventor: Shouhua Xiao , Xiaodong Zhu
- Applicant: XUANZHU BIOPHARMACEUTICAL CO., LTD. , BEIJING XUANZHU COMBIO CO., LTD.
- Applicant Address: CN Shijiazhuang; CN Beijing
- Assignee: XUANZHU BIOPHARMACEUTICAL CO., LTD.,BEIJING XUANZHU COMBIO CO., LTD.
- Current Assignee: XUANZHU BIOPHARMACEUTICAL CO., LTD.,BEIJING XUANZHU COMBIO CO., LTD.
- Current Assignee Address: CN Shijiazhuang; CN Beijing
- Agency: Harness, Dickey & Pierce, P.L.C.
- International Application: PCT/US2018/026759 WO 20180409
- International Announcement: WO2018/191188 WO 20181018
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/32
Abstract:
The present invention relates to bispecific or multi-specific antibody molecules with two or more paratopes. At least one paratope is Fv or scFv, while the other paratope is in a mono-valent or bivalent Fab. These novel molecules also have an Fc moiety that allows extended half-life in vivo.
Information query
