Invention Grant
- Patent Title: Benzimidazole derivatives and their uses
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Application No.: US16754349Application Date: 2018-10-18
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Publication No.: US11332459B2Publication Date: 2022-05-17
- Inventor: Michael D. Bartberger , Nagasree Chakka , Hua Gao , Angel Guzman-Perez , Daniel B. Horne , Zihao Hua , Madeleine Kieffer , Daniel C. H. Lin , Benjamin Charles Milgram , Jane Panteleev , Laurie Schenkel , John Stellwagen , Matthew Weiss , Ryan D. White , Wei Zhao
- Applicant: TEIJIN PHARMA LIMITED
- Applicant Address: JP Tokyo
- Assignee: TEIJIN PHARMA LIMITED
- Current Assignee: TEIJIN PHARMA LIMITED
- Current Assignee Address: JP Tokyo
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo PC
- International Application: PCT/US2018/056484 WO 20181018
- International Announcement: WO2019/079578 WO 20190425
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/4545 ; C07D401/04 ; C07D403/04 ; C07D413/14 ; C07D471/04 ; C07D471/10 ; C07D498/04
Abstract:
The present invention relates to inhibitors of Transient Receptor Potential Channel 6 (TRPC6) protein activity. The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.
Public/Granted literature
- US20200308145A1 BENZIMIDAZOLE DERIVATIVES AND THEIR USES Public/Granted day:2020-10-01
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