Invention Grant
- Patent Title: Process for the preparation of a sulfonamide structured kinase inhibitor
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Application No.: US16953468Application Date: 2020-11-20
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Publication No.: US11332460B2Publication Date: 2022-05-17
- Inventor: Oskari Karjalainen , Pekka Pietikäinen
- Applicant: ORION CORPORATION
- Applicant Address: FI Espoo
- Assignee: ORION CORPORATION
- Current Assignee: ORION CORPORATION
- Current Assignee Address: FI Espoo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: FI20175272 20170323
- Main IPC: C07D403/04
- IPC: C07D403/04

Abstract:
The present disclosure relates to an improved process for the preparation of a sulfonamide structured kinase inhibitor, namely N-(2′,4′-difluoro-5-(5-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)-[1,1′-biphenyl]-3-yl)cyclopropanesulfonamide (1A) and pharmaceutically acceptable salts thereof. Compound of formula (1A) is a selective inhibitor of FGFR/VEGFR kinase families and is useful in the treatment of cancer.
Public/Granted literature
- US20210139462A1 PROCESS FOR THE PREPARATION OF A SULFONAMIDE STRUCTURED KINASE INHIBITOR Public/Granted day:2021-05-13
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