Invention Grant
- Patent Title: Immunotherapeutic modulation of amyloidogenic disease using non-fibrillogenic, non-amyloidogenic polymerized proteins and peptides
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Application No.: US15933146Application Date: 2018-03-22
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Publication No.: US11332506B2Publication Date: 2022-05-17
- Inventor: Thomas M. Wisniewski , Fernando Goni
- Applicant: New York University
- Applicant Address: US NY New York
- Assignee: New York University
- Current Assignee: New York University
- Current Assignee Address: US NY New York
- Agency: Troutman Pepper Hamilton Sanders LLP (Rochester)
- Main IPC: C07K14/47
- IPC: C07K14/47 ; A61K39/00 ; G01N33/68 ; A61K9/00 ; C07K16/18

Abstract:
The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
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