Invention Grant
- Patent Title: Glycan-based antibody-drug conjugates
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Application No.: US15493720Application Date: 2017-04-21
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Publication No.: US11332544B2Publication Date: 2022-05-17
- Inventor: Robert Davidson , Bing Gong
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent John David Reilly; Anna Cocuzzo
- Main IPC: C07K16/32
- IPC: C07K16/32 ; C12P21/00 ; A61K47/68 ; C07K16/00 ; A61K39/00
Abstract:
Genetically engineered antibodies containing non-native N-glycosylated sites, preparation of the antibodies in yeast and fungi, site-specific conjugation of drugs to these antibodies, and methods of treatment utilizing these antibodies are described herein.
Public/Granted literature
- US20170362338A1 GLYCAN-BASED ANTIBODY-DRUG CONJUGATES Public/Granted day:2017-12-21
Information query
