A method and an apparatus of cooperating with a plurality of base stations in a wireless communication system. A cloud cell is configured with a plurality of base stations that cooperate with each other for a mobile station and synchronizes user contexts for serving the mobile station among the plurality of base stations included in the cloud cell, and the plurality of base stations cooperate with each other to provide a communication service to the mobile station. The present disclosure reduces generation of a handover when the mobile station moves between base stations, and increases the data yield of the mobile station by transmitting and receiving data in cooperation with base stations in a cloud cell at a shaded area or a cell border.