Invention Grant
- Patent Title: Pharmaceutical combinations comprising a histone deacetylase inhibitor and a CD38 inhibitor and methods of use thereof
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Application No.: US16463247Application Date: 2017-11-22
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Publication No.: US11337975B2Publication Date: 2022-05-24
- Inventor: Steven Norman Quayle , Simon Stewart Jones , Teru Hideshima , Kenneth C. Anderson
- Applicant: Acetylon Pharmaceuticals, Inc.
- Applicant Address: US MA Boston
- Assignee: Acetylon Pharmaceuticals, Inc.
- Current Assignee: Acetylon Pharmaceuticals, Inc.
- Current Assignee Address: US MA Boston
- Agency: Lathrop GPM LLP
- Agent Brian C. Trinque
- International Application: PCT/US2017/063106 WO 20171122
- International Announcement: WO2018/098348 WO 20180531
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61P35/00 ; A61K31/573 ; A61K39/395 ; C07K16/28 ; A61K45/06 ; A61K31/454 ; C07D239/42

Abstract:
The present disclosure relates to a pharmaceutical combination comprising (a) a histone deacetylase inhibitor and (b) a CD38 inhibitor, including combined preparations and pharmaceutical compositions thereof; uses of such combination in the treatment or prevention of cancer; and methods of treating or preventing cancer in a subject comprising administering a therapeutically effective amount of such combination.
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