Invention Grant
- Patent Title: Treprostinil derivative compounds and methods of using same
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Application No.: US16927601Application Date: 2020-07-13
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Publication No.: US11339139B2Publication Date: 2022-05-24
- Inventor: Cyrus K. Becker , Meenakshi S. Venkatraman , Xiaoming Zhang
- Applicant: CORSAIR PHARMA, INC.
- Applicant Address: US CA South San Francisco
- Assignee: CORSAIR PHARMA, INC.
- Current Assignee: CORSAIR PHARMA, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: The Marbury Law Group PLLC
- Main IPC: C07D313/00
- IPC: C07D313/00 ; C07C69/712 ; C07D317/40 ; C07D321/00 ; C07D257/06 ; C07D263/24 ; C07D265/30 ; C07D295/088 ; C07D211/60 ; C07D295/145 ; C07D307/20 ; C07C219/16 ; C07C235/20 ; C07D453/02 ; C07C59/54 ; C07C69/734 ; C07C235/34 ; C07D207/08 ; C07D263/26 ; C07D317/34 ; A61K9/70 ; A61K31/165 ; A61K31/216 ; A61K31/335 ; C07C59/31

Abstract:
Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
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