![Crystalline forms of the CXCR7 receptor antagonist (3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-phenyl)-isoxazole-3-carbonyl]-amino}-piperidine-3-carboxylic acid (1-pyrimidin-2-yl-cyclopropyl)-amide](/docs/US/2022-05-24/US11339148B2/abs.jpg.600x600.jpg)
- Patent Title: Crystalline forms of the CXCR7 receptor antagonist (3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-phenyl)-isoxazole-3-carbonyl]-amino}-piperidine-3-carboxylic acid (1-pyrimidin-2-yl-cyclopropyl)-amide
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Application No.: US16964885Application Date: 2019-01-25
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Publication No.: US11339148B2Publication Date: 2022-05-24
- Inventor: Philippe Guerry , Markus Von Raumer
- Applicant: IDORSIA PHARMACEUTICALS LTD.
- Applicant Address: CH Allschwil
- Assignee: IDORSIA PHARMACEUTICALS LTD.
- Current Assignee: IDORSIA PHARMACEUTICALS LTD.
- Current Assignee Address: CH Allschwil
- Agency: Culhane Meadow, LLP
- Agent Jeff B. Vockrodt
- Priority: WOPCT/EP2018/051938 20180126
- International Application: PCT/EP2019/051819 WO 20190125
- International Announcement: WO2019/145460 WO 20190108
- Main IPC: C07D413/14
- IPC: C07D413/14
![Crystalline forms of the CXCR7 receptor antagonist (3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-phenyl)-isoxazole-3-carbonyl]-amino}-piperidine-3-carboxylic acid (1-pyrimidin-2-yl-cyclopropyl)-amide](/abs-image/US/2022/05/24/US11339148B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to crystalline forms of (3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-phenyl)-isoxazole-3-carbonyl]-amino}-piperidine-3-carboxylic acid (1-pyrimidin-2-yl-cyclopropyl)-amide; processes for the preparation thereof, pharmaceutical compositions containing such crystalline forms, pharmaceutical compositions prepared from such crystalline forms, and their use as a medicament, especially as CXCR7 receptor modulators.
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