Invention Grant
- Patent Title: Triazolo pyridines as modulators of gamma-secretase
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Application No.: US16955093Application Date: 2018-12-18
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Publication No.: US11339161B2Publication Date: 2022-05-24
- Inventor: Niklas Heine , Christian Eickmeier , Kai Gerlach , Ulrike Gross
- Applicant: Boehringer Ingelheim International GmbH
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent David L. Kershner
- Priority: EP17208420 20171219
- International Application: PCT/EP2018/085364 WO 20181218
- International Announcement: WO2019/121596 WO 20190627
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P25/28
Abstract:
The present invention relates to triazolo pyridines of formula (II) and their use as modulators of #-secretase. In particular, the present invention relates to compounds which interfere with #-secretase and/or its substrate and therefore modulate the formation of Aβ peptides. Accordingly these compounds can be used for the treatment of Aβ-related pathologies, e.g. Alzheimer's disease.
Public/Granted literature
- US20210017173A1 TRIAZOLO PYRIDINES AS MODULATORS OF GAMMA-SECRETASE Public/Granted day:2021-01-21
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