Invention Grant
- Patent Title: Chimeric NK receptor and methods for treating cancer
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Application No.: US16458740Application Date: 2019-07-01
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Publication No.: US11339199B2Publication Date: 2022-05-24
- Inventor: Tong Zhang , Charles L. Sentman
- Applicant: TRUSTEES OF DARTMOUTH COLLEGE
- Applicant Address: US NH Hanover
- Assignee: TRUSTEES OF DARTMOUTH COLLEGE
- Current Assignee: TRUSTEES OF DARTMOUTH COLLEGE
- Current Assignee Address: US NH Hanover
- Agency: Baker, Donelson, Bearman, Caldwell & Berkowitz PC
- Agent Robin L. Teskin
- Main IPC: A61K35/17
- IPC: A61K35/17 ; C07K14/705 ; A61K38/10 ; C07K14/715 ; A61K45/06
Abstract:
The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provided.
Information query
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