Invention Grant
- Patent Title: α-synuclein protofibril-binding antibodies
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Application No.: US17359212Application Date: 2021-06-25
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Publication No.: US11339212B2Publication Date: 2022-05-24
- Inventor: Eva Nordström , Jessica Sigvardson , Patrik Nygren
- Applicant: BioArctic AB
- Applicant Address: SE Stockholm
- Assignee: BioArctic AB
- Current Assignee: BioArctic AB
- Current Assignee Address: SE Stockholm
- Agency: Foley Hoag LLP
- Main IPC: C07K16/18
- IPC: C07K16/18
Abstract:
The present disclosure is based, in part, on the discovery of antibodies that selectively targets human α-synuclein aggregates such as oligomers/protofibrils, such as BAN0805. BAN0805 has a lower tendency to bind to the undesired monomeric α-synuclein target as compared to mouse monoclonal antibody mAb47.
Public/Granted literature
- US20210403542A1 alpha-SYNUCLEIN PROTOFIBRIL-BINDING ANTIBODIES Public/Granted day:2021-12-30
Information query
