Invention Grant
- Patent Title: Methods and agents for the diagnosis and treatment of hepatocellular carcinoma
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Application No.: US16450730Application Date: 2019-06-24
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Publication No.: US11339217B2Publication Date: 2022-05-24
- Inventor: Kuo-Jang Kao , Andrew T. Huang
- Applicant: Circular Commitment Company
- Applicant Address: TW Taipei
- Assignee: Circular Commitment Company
- Current Assignee: Circular Commitment Company
- Current Assignee Address: TW Taipei
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07K16/00 ; C07K16/28 ; A61K51/10 ; G01N33/574 ; C07K16/30 ; A61K39/395 ; A61K45/06 ; G01N33/577 ; C12Q1/6886
Abstract:
The present invention relates to methods of diagnosing and methods of treating hepatocellular carcinoma in a subject. The invention also relates to antagonists of PLVAP proteins, such as antibodies that specifically bind PLVAP proteins, as well as compositions and kits comprising antagonists of PLVAP proteins. The invention further relates to humanized antibodies that specifically bind PLVAP protein.
Public/Granted literature
- US20190309062A1 Methods And Agents For The Diagnosis And Treatment Of Hepatocellular Carcinoma Public/Granted day:2019-10-10
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