Invention Grant
- Patent Title: Bispecific antibody constructs and methods of use
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Application No.: US16759964Application Date: 2018-10-30
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Publication No.: US11339221B2Publication Date: 2022-05-24
- Inventor: Paul Mathew
- Applicant: Tufts Medical Center, Inc.
- Applicant Address: US MA Boston
- Assignee: Tufts Medical Center, Inc.
- Current Assignee: Tufts Medical Center, Inc.
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2018/058146 WO 20181030
- International Announcement: WO2019/089544 WO 20190509
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; C07K16/00 ; C07K16/46 ; C07K16/28 ; A61P35/00 ; C12N15/63
Abstract:
The present invention relates to bispecific antibody constructs that specifically bind both integrin alpha-V and integrin α5 (e.g., α5β1) and methods of making and using those constructs to treat cancer or other pathological conditions involving these integrins.
Public/Granted literature
- US20200277382A1 BISPECIFIC ANTIBODY CONSTRUCTS AND METHODS OF USE Public/Granted day:2020-09-03
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