Invention Grant
- Patent Title: Malate dehyrogenases
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Application No.: US16999962Application Date: 2020-08-21
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Publication No.: US11339379B2Publication Date: 2022-05-24
- Inventor: Alrik Pieter Los , Rene Marcel De Jong , Remko Tsjibbe Winter , Ben Den Dulk
- Applicant: DSM IP ASSETS B.V.
- Applicant Address: NL Heerlen
- Assignee: DSM IP ASSETS B.V.
- Current Assignee: DSM IP ASSETS B.V.
- Current Assignee Address: NL Heerlen
- Agency: McBee Moore & Vanik IP, LLC
- Priority: EP16179315 20160713
- Main IPC: C12N9/04
- IPC: C12N9/04 ; C12P7/46 ; C12N1/20 ; C12N15/00 ; C12N1/14 ; C12N1/18 ; C12R1/865

Abstract:
The present invention relates to a recombinant host cell which is capable of producing a dicarboxylic acid and which comprises a mutant malate dehydrogenase resulting in an increased production of the dicarboxylic acid. The invention also relates to a process for producing a dicarboxylic acid, which method comprises fermenting said recombinant host cell in a suitable fermentation medium and producing the dicarboxylic acid.
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