Invention Grant
- Patent Title: Modified nucleic acid editing systems for tethering donor DNA
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Application No.: US16363642Application Date: 2019-03-25
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Publication No.: US11339385B2Publication Date: 2022-05-24
- Inventor: Roy Geoffrey Sargent
- Applicant: GeneTether, Inc.
- Applicant Address: US CA San Francisco
- Assignee: GeneTether, Inc.
- Current Assignee: GeneTether, Inc.
- Current Assignee Address: US CA San Francisco
- Agent Dennis A. Bennett; Chris Marion; Stephanie M. Greer
- Main IPC: C12N9/22
- IPC: C12N9/22 ; C07K14/47 ; C12N15/11 ; A61K38/00 ; C12N9/96 ; C12N15/90 ; C12N15/113 ; C12N15/62 ; C12N15/63
Abstract:
The technology relates to a composition for tethering donor DNA to a nuclease, the composition comprising a nucleic acid comprising donor DNA and a consensus sequence for a DNA binding domain; and at least one of: a fusion protein comprising a nuclease coupled to a DNA binding domain for binding the consensus sequence; and a nucleic acid encoding the fusion protein.
Public/Granted literature
- US20190309275A1 MODIFIED NUCLEIC ACID EDITING SYSTEMS FOR TETHERING DONOR DNA Public/Granted day:2019-10-10
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