Invention Grant
- Patent Title: Nuclease with enhanced efficiency of genome editing
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Application No.: US15754589Application Date: 2016-08-22
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Publication No.: US11339408B2Publication Date: 2022-05-24
- Inventor: Ruby Yanru Tsai , Ling-jie Kong , Jingyuan Cao
- Applicant: APPLIED STEMCELL, INC.
- Applicant Address: US CA Milpitas
- Assignee: APPLIED STEMCELL, INC.
- Current Assignee: APPLIED STEMCELL, INC.
- Current Assignee Address: US CA Milpitas
- Agency: Jun He Law Offices P.C.
- Agent Yi Zhang
- International Application: PCT/US2016/047937 WO 20160822
- International Announcement: WO2017/031483 WO 20170223
- Main IPC: C12N9/22
- IPC: C12N9/22 ; C12N15/113 ; C12N15/63 ; C12N15/90 ; C12N15/11
Abstract:
The present disclosure provides a composition comprising a site-specific nuclease domain capable of cleaving a target DNA sequence; and a sequence-specific DNA binding domain capable of specifically binding to a recognition DNA sequence, wherein the site-specific nuclease domain operably links to the sequence-specific DNA binding domain.
Public/Granted literature
- US20180216135A1 NUCLEASE WITH ENHANCED EFFICIENCY OF GENOME EDITING Public/Granted day:2018-08-02
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