Invention Grant
- Patent Title: Method for detecting Tac2 gene sensitive to low-level ionizing radiation, and gene detected by the method
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Application No.: US16193901Application Date: 2018-11-16
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Publication No.: US11339445B2Publication Date: 2022-05-24
- Inventor: Hee Sun Kim , Seung Jin Choi , Moo Hyun Choi , Jin Jong Bong , Seok Cheol Shin
- Applicant: KOREA HYDRO & NUCLEAR POWER CO., LTD
- Applicant Address: KR Gyeongju
- Assignee: KOREA HYDRO & NUCLEAR POWER CO., LTD
- Current Assignee: KOREA HYDRO & NUCLEAR POWER CO., LTD
- Current Assignee Address: KR Gyeongju
- Priority: KR10-2012-0049560 20120510
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886 ; C12Q1/6883

Abstract:
A method for detecting genes sensitive to low-level ionizing radiation and genes detected by the method. More specifically, genes sensitive to low-level ionizing radiation and related to suppressing thymic cancer, discovered in a carcinogenic entity and verified in a normal entity are detected by subjecting a cancerous AKR/J mouse and a normal ICR mouse to low-level radiation. Thymus is collected therefrom, immunogenic and apoptotic genes are classified via microarray processing of the thymus. The genes are amplified and the levels of gene expression are measured. Thus, a gene having a specific reaction to radiation can be accurately detected by preventing the interference of confounding variables.
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