Invention Grant
- Patent Title: Catalytic particles for increased sensitivity in lateral flow immunoassays
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Application No.: US15455045Application Date: 2017-03-09
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Publication No.: US11340217B2Publication Date: 2022-05-24
- Inventor: David A. Kidwell
- Applicant: The Government of the United States of America, as represented by the Secretary of the Navy
- Applicant Address: US VA Arlington
- Assignee: The Government of the United States of America, as represented by the Secretary of the Navy
- Current Assignee: The Government of the United States of America, as represented by the Secretary of the Navy
- Current Assignee Address: US VA Arlington
- Agency: US Naval Research Laboratory
- Agent Rebecca L. Forman
- Main IPC: G01N33/558
- IPC: G01N33/558 ; G01N33/53 ; G01N33/543 ; G01N11/02 ; G01N33/532
Abstract:
The present invention provides a method for preparing colloidal palladium nanoparticles and using them for increased sensitivity in lateral flow immunoassays. Glutaraldehyde is used in preparing the colloidal palladium that allows rapid attachment of biomolecules. Colloidal palladium nanoparticles are labeled with a protein, such as a biomolecule or an antibody. These labeled colloidal palladium particles catalytically develop a dye to detect the presence of an analyte.
Public/Granted literature
- US20180052153A1 CATALYTIC PARTICLES FOR INCREASED SENSITIVITY IN LATERAL FLOW IMMUNOASSAYS Public/Granted day:2018-02-22
Information query
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