Invention Grant
- Patent Title: Use of molecular marker Dkk-3 associated with muscle atrophy
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Application No.: US15569981Application Date: 2016-04-28
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Publication No.: US11340221B2Publication Date: 2022-05-24
- Inventor: Ping Hu , Jie Yin
- Applicant: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
- Applicant Address: CN Shanghai
- Assignee: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
- Current Assignee: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
- Current Assignee Address: CN Shanghai
- Agency: Lee & Hayes, P.C.
- Priority: CN201510215819.4 20150429
- International Application: PCT/CN2016/080441 WO 20160428
- International Announcement: WO2016/173501 WO 20161103
- Main IPC: C12Q1/6883
- IPC: C12Q1/6883 ; C12Q1/6851 ; C12Q1/6876 ; C12Q1/6806 ; C12Q1/686 ; G01N33/566 ; G01N33/68 ; C12N5/077 ; C12Q1/02 ; G01N33/50
Abstract:
Disclosed are a protein molecular marker Dkk-3 protein associated with age-related muscle atrophy and the use thereof in the diagnosis of age-related muscle atrophy. The expression level of the Dkk-3 protein in amyotrophic cells is significantly higher than that in normal myocytes or tissues, and thus the Dkk-3 protein can be used as an effective marker for the detection of age-related muscle atrophy.
Public/Granted literature
- US20180156794A1 Filtering Of Protein Molecular Marker DKK-3 Related To Muscle Atrophy, And Application Thereof Public/Granted day:2018-06-07
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