Invention Grant
- Patent Title: Squalene epoxidase in the diagnosis and treatment of non-alcoholic fatty liver diseases
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Application No.: US15911042Application Date: 2018-03-02
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Publication No.: US11340226B2Publication Date: 2022-05-24
- Inventor: Jun Yu , Dabin Liu , Chi-Chun Wong
- Applicant: The Chinese University of Hong Kong
- Applicant Address: CN Hong Kong
- Assignee: The Chinese University of Hong Kong
- Current Assignee: The Chinese University of Hong Kong
- Current Assignee Address: CN Hong Kong
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: G01N33/573
- IPC: G01N33/573 ; G01N33/68 ; C12Q1/26 ; A61K49/16
Abstract:
The present invention provides a method for providing a diagnosis or prognosis of a non-alcoholic fatty liver disease (NAFLD) in a subject by detecting expression level of the Squalene Epoxidase (SQLE) gene. A kit and device useful for such methods are also provided. In addition, the present invention provides a method for treating NAFLD by suppressing SQLE gene expression or activity.
Public/Granted literature
- US20190271698A1 SQUALENE EPOXIDASE IN THE DIAGNOSIS AND TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASES Public/Granted day:2019-09-05
Information query
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