Techniques to facilitate synchronization of industrial assets in an industrial automation environment are disclosed herein. In at least one implementation, a computing system receives time-series industrial process data associated with a plurality of process subsystems of an industrial automation process. The time-series industrial process data is fed into a machine learning model associated with the industrial automation process to dynamically generate a process duration prediction for a first one of the process subsystems and responsively determine an updated set point for a second one of the process subsystems based on the process duration prediction for the first one of the process subsystems. The updated set point for the second one of the process subsystems is provided to an industrial controller associated with the second one of the process subsystems.