Methods or systems (7000) are implemented for treatment with or monitoring use of respiratory pressure therapy device(s). The device may be for a respiratory disorder. A processor, such as a processor of a server communicating with the therapy device, may analyse data relating to respiratory therapy delivered by the device. The processor may generate data in the processor representing a prediction, such as compliance prediction(s), about progress of therapy based on the analysis. The processor may select an action to improve therapy based on data representing the prediction. The processor may take or prompt selected action to improve the therapy. In some cases, a processor may analyse usage data concerning a period of days with a therapy device and generate compliance prediction indicators based on the analysis. The indicators indicate whether compliance will be likely. The processor may recommend engagement action to improve compliance based on evaluation of the indicators.