The embodiments of the present application discloses a radio resource configuration method, a network-side device and a user-side device. The method includes: receiving configuration information for indicating to perform activation or deactivation of a radio resource configuration; wherein the radio resource configuration includes a CORESET configuration and/or a quasi co-location (QCL) related configuration; activating or deactivating the radio resource configuration according to the configuration information. In the application, the activation or deactivation of the radio resource configuration is achieved; moreover, the rapid activation or deactivation of the radio resource configuration is achieved; it is ensured that the times known by the network-side device and the user-side device, at which the activation or deactivation operation on the user-side device is performed, are consistent; and the utilization efficiency of air interface resources is improved.