The invention relates to an endoscope shaft 1 having a layered structure. In this shaft 1, formed as a curved or non-curved hollow cylinder, various layers succeed and enclose one another radially over the entire length or a substantial part of the length of the shaft. The shaft has an inner layer 2 of plastic, and an outer layer 3 of plastic enclosing the inner layer 2, and a structuring layer 4 in the transition region 5 of the inner layer and the outer layer 3. The plastics of the inner layer and of the outer layer 3 are different, and the inner layer and the outer layer 3 mesh together in the transition region 5. Thus, the inner layer and the outer layer 3 can connect to each other particularly well, and a delamination of the inner layer and of the outer layer 3 can thus be prevented. This is specifically because the interface between the inner layer and the outer layer 3 is enlarged, in relation to the prior art, by the mutual meshing 6. Moreover, the geometry of the mutual meshing creates a particularly stable and durable mechanical connection between the layers 2, 3 and 4, which allows forces to be transmitted from one of the layers 2, 3, 4 to another in a particularly reliable and permanent manner, as a result of which undesired delamination is prevented, in particular in flexible endoscope shafts 1. The invention further relates to a method for producing such an endoscope shaft 1 according to the invention.