A patient support apparatus, such as a bed, cot, recliner, operating table, stretcher, or the like, includes a control panel with multiple controls for controlling functions of the patient support apparatus. A control system disables at least a first control and changes an illumination state of a backlight when the patient support apparatus is in a particular state. In some embodiments, the particular state is the arming of an exit detection system and/or the deactivation of a brake on the patient support apparatus. The particular state may also or alternatively be tied to a particular mode of the patient support apparatus, such as a diagnostic mode, a maintenance mode, and/or a normal mode. The control system may also never illuminate a first icon on the patient support apparatus if it was initially configured in a particular manner, such as being intended for sale in a particular geographic market.