Invention Grant
- Patent Title: Compound having anticancer activity and preparation method and application
-
Application No.: US16461828Application Date: 2017-11-17
-
Publication No.: US11351151B2Publication Date: 2022-06-07
- Inventor: John Gong , Yihui Lin , Fengqing Li , Fangqiang Tang
- Applicant: 3D Medicines (Beijing) Co., Ltd.
- Applicant Address: CN Beijing
- Assignee: 3D Medicines (Beijing) Co., Ltd.
- Current Assignee: 3D Medicines (Beijing) Co., Ltd.
- Current Assignee Address: CN Beijing
- Agency: Grogan, Tuccillo & Vanderleeden LLP
- Priority: CN201611027194.X 20161117,CN201710327784.2 20170510
- International Application: PCT/CN2017/111653 WO 20171117
- International Announcement: WO2018/090975 WO 20180524
- Main IPC: A61K31/416
- IPC: A61K31/416 ; A61P35/00

Abstract:
The present invention provides a compound exemplified by Formula I: a process for its preparation and the use of a medicament for the treatment of cancer. The compound of the present invention has an inhibitory effect on various cancer cells and can be biologically converted into the active drug Linifanib in vitro (in liver homogenate and spleen homogenate) to inhibit the proliferation of tumor cells, especially liver cancer cells, at a lower dose.
Public/Granted literature
- US20200038371A1 COMPOUND HAVING ANTICANCER ACTIVITY AND PREPARATION METHOD AND APPLICATION Public/Granted day:2020-02-06
Information query
IPC分类: