Invention Grant
- Patent Title: Compositions and methods of modulating s-nitrosylation
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Application No.: US15533268Application Date: 2015-12-07
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Publication No.: US11351155B2Publication Date: 2022-06-07
- Inventor: Jonathan Stamler
- Applicant: CASE WESTERN RESERVE UNIVERSITY
- Applicant Address: US OH Cleveland
- Assignee: CASE WESTERN RESERVE UNIVERSITY
- Current Assignee: CASE WESTERN RESERVE UNIVERSITY
- Current Assignee Address: US OH Cleveland
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- International Application: PCT/US2015/064308 WO 20151207
- International Announcement: WO2016/090373 WO 20160609
- Main IPC: A61K31/4184
- IPC: A61K31/4184 ; A61P9/10 ; A61K45/06 ; A61K31/433 ; A61K31/145 ; A61K31/423 ; A61K31/403 ; A61K31/675
Abstract:
A method of treating disorders associated with NO/SNO deficiency or benefiting from increased SNO in a subject in need thereof includes administering to the subject an ADH inhibitor, AKR inhibitor, SNO-CoAR inhibitor, and/or SNO-CoA at an amount(s) effective to promote S-nitrosylation of proteins in the subject.
Public/Granted literature
- US20170360755A1 COMPOSITIONS AND METHODS OF MODULATING S-NITROSYLATION Public/Granted day:2017-12-21
Information query
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