Invention Grant
- Patent Title: Effective vaccination against porcine reproductive and respiratory syndrome (PRRS) virus prior to weaning
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Application No.: US16530019Application Date: 2019-08-02
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Publication No.: US11351239B2Publication Date: 2022-06-07
- Inventor: Jay Gregory Calvert , Robert G. Ankenbauer , Jacqueline Gayle Marx , Douglas S. Pearce , Marcia L. Keith
- Applicant: Zoetis Services LLC
- Applicant Address: US NJ Parsippany
- Assignee: Zoetis Services LLC
- Current Assignee: Zoetis Services LLC
- Current Assignee Address: US NJ Parsippany
- Agent Vyacheslav Vasilyev
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C12N7/00 ; A61K39/00
Abstract:
The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components. Vaccines comprising the genetically modified virus and polynucleotides and a diagnostic kit to distinguish between naturally infected and vaccinated animals are also provided.
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