Invention Grant
- Patent Title: Type II topoisomerase inhibitors and methods of making and using thereof
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Application No.: US16606044Application Date: 2018-04-17
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Publication No.: US11352349B2Publication Date: 2022-06-07
- Inventor: Mark Mitton-Fry
- Applicant: Ohio State Innovation Foundation
- Applicant Address: US OH Columbus
- Assignee: Ohio State Innovation Foundation
- Current Assignee: Ohio State Innovation Foundation
- Current Assignee Address: US OH Columbus
- Agency: Meunier Carlin & Curfman LLC
- International Application: PCT/US2018/028001 WO 20180417
- International Announcement: WO2018/195098 WO 20181025
- Main IPC: C07D405/14
- IPC: C07D405/14 ; C07D405/06 ; C07D409/14 ; C07D491/052 ; C07D491/056 ; C07D498/04 ; C07D513/04

Abstract:
Disclosed are Type II Topoisomerase Inhibitors, analogs thereof, pharmaceutical compositions thereof and methods of making and using these compounds and compositions. Methods of using the disclosed compounds to treat infections, such as MRSA, MDR P. aeruginosa, and other pathogens are also described.
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