Invention Grant
- Patent Title: Treatment of haematological malignancies
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Application No.: US16627230Application Date: 2018-06-28
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Publication No.: US11352389B2Publication Date: 2022-06-07
- Inventor: Marieke Griffioen , J. H. Frederik Falkenburg
- Applicant: ACADEMISCH ZIEKENHUIS LEIDEN (H.O.D.N. LEIDS UNIVERSITAIR MEDISCH CENTRUM)
- Applicant Address: NL Leiden
- Assignee: ACADEMISCH ZIEKENHUIS LEIDEN (H.O.D.N. LEIDS UNIVERSITAIR MEDISCH CENTRUM)
- Current Assignee: ACADEMISCH ZIEKENHUIS LEIDEN (H.O.D.N. LEIDS UNIVERSITAIR MEDISCH CENTRUM)
- Current Assignee Address: NL Leiden
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: NL2019156 20170630,NL2020602 20180316
- International Application: PCT/NL2018/050421 WO 20180628
- International Announcement: WO2019/004831 WO 20190103
- Main IPC: C07K7/06
- IPC: C07K7/06 ; A61P35/02 ; A61K35/17 ; A61K35/761 ; C07K14/47 ; C07K14/725 ; C12N15/86 ; A61K39/00
Abstract:
Novel nucleic acid sequences, vectors, modified cells, peptides and pharmaceutical compositions are provided that are useful in the treatment of human subjects having a ΔNPM1 positive haematological malignancy. Corresponding methods and uses are also provided.
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