Invention Grant
- Patent Title: Opioid receptor binding agents and uses thereof
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Application No.: US16355442Application Date: 2019-03-15
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Publication No.: US11352422B2Publication Date: 2022-06-07
- Inventor: Jan Steyaert , Toon Laeremans , Els Pardon , Brian Kobilka , Aashish Manglik
- Applicant: VIB VZW , VRIJE UNIVERSITEIT BRUSSEL , THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
- Applicant Address: BE Ghent; BE Brussels; US CA Palo Alto
- Assignee: VIB VZW,VRIJE UNIVERSITEIT BRUSSEL,THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
- Current Assignee: VIB VZW,VRIJE UNIVERSITEIT BRUSSEL,THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
- Current Assignee Address: BE Ghent; BE Brussels; US CA Palo Alto
- Agency: Patent Law Works, LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K14/705 ; C07K14/72 ; G01N33/50 ; G01N33/68
Abstract:
Agents that specifically bind to an opioid receptor in a conformationally specific way can be used to induce a conformational change in the receptor. Such agents have therapeutic applications and can be used in X-ray crystallography studies of the receptor. Such agents can also be used to improve drug discovery via compound screening and/or structure-based drug design.
Public/Granted literature
- US20190338024A1 Opioid Receptor Binding Agents and Uses Thereof Public/Granted day:2019-11-07
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