Invention Grant
- Patent Title: Modulation of immune response using BTLA agonist antibodies
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Application No.: US15570013Application Date: 2016-04-29
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Publication No.: US11352428B2Publication Date: 2022-06-07
- Inventor: Carl F. Ware , John Sedy , Paula Norris
- Applicant: Sanford Burnham Prebys Medical Discovery Institute
- Applicant Address: US CA La Jolla
- Assignee: Sanford Burnham Prebys Medical Discovery Institute
- Current Assignee: Sanford Burnham Prebys Medical Discovery Institute
- Current Assignee Address: US CA La Jolla
- Agency: McNeill Baur PLLC
- International Application: PCT/US2016/030138 WO 20160429
- International Announcement: WO2016/176583 WO 20161103
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P37/00 ; A61P29/00 ; C07K14/715 ; A61K39/00
Abstract:
The present invention relates to the seminal discovery that BTLA agonist antibodies modulate the immune system. Specifically, the present invention provides antibodies which bind BTLA in the activated state enhancing BTLA signaling. The present invention further provides methods of treating immune and inflammatory diseases and disorders with a BTLA agonist antibody.
Public/Granted literature
- US20180155426A1 MODULATION OF IMMUNE RESPONSE USING BTLA AGONIST ANTIBODIES Public/Granted day:2018-06-07
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