Invention Grant
- Patent Title: Conjugates enhancing total cellular accumulation
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Application No.: US16085141Application Date: 2017-03-15
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Publication No.: US11352437B2Publication Date: 2022-06-07
- Inventor: Simon Beaudoin , Jeffrey Victor Leyton
- Applicant: DEFENCE THERAPEUTICS INC.
- Applicant Address: CA Vancouver
- Assignee: DEFENCE THERAPEUTICS INC.
- Current Assignee: DEFENCE THERAPEUTICS INC.
- Current Assignee Address: CA Vancouver
- Agency: Norton Rose Fulbright Canada LLP
- International Application: PCT/CA2017/050337 WO 20170315
- International Announcement: WO2017/156630 WO 20170921
- Main IPC: A61K47/64
- IPC: A61K47/64 ; A61K47/68 ; C07K16/32 ; C07K16/30 ; C12N15/11 ; A61K47/54 ; C07J9/00
Abstract:
The present description relates to a conjugated compound comprising cholic acid (ChAc) or a variant thereof, the ChAc conjugated to a non-cell penetrating peptide comprising a nuclear localization sequence (NLS) conjugated to a compound of interest.
Public/Granted literature
- US20190077879A1 CONJUGATES ENHANCING TOTAL CELLULAR ACCUMULATION Public/Granted day:2019-03-14
Information query
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