Invention Grant
- Patent Title: Method for culturing myogenic cells, cultures obtained therefrom, screening methods, and cell culture medium
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Application No.: US16300869Application Date: 2017-05-12
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Publication No.: US11352605B2Publication Date: 2022-06-07
- Inventor: Wilhelmus Wenceslaus Matthias Pijnappel , Antje Tjitske van der Ploeg , Erik van der Wal
- Applicant: Erasmus University Medical Center Rotterdam
- Applicant Address: NL Rotterdam
- Assignee: Erasmus University Medical Center Rotterdam
- Current Assignee: Erasmus University Medical Center Rotterdam
- Current Assignee Address: NL Rotterdam
- Agency: Dentons US LLP
- Priority: EP16169396 20160512
- International Application: PCT/NL2017/050298 WO 20170512
- International Announcement: WO2017/196175 WO 20171116
- Main IPC: C12N5/077
- IPC: C12N5/077 ; C12N5/074 ; C12N5/00 ; C12Q1/02
Abstract:
The invention is in the field of cell culturing. More specifically, it is in the field of generating and expanding myogenic cells from induced pluripotent stem (i PS) cells. The invention relates inter alia to cells generated and expanded via such a method, a growth medium specifically suited for the purpose of expanding isolated myogenic cells, and methods for screening compounds on cell structures such as myotubes and myofibers.
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