Invention Grant
- Patent Title: Non-LTR-retroelement reverse transcriptase and uses thereof
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Application No.: US16753201Application Date: 2018-10-03
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Publication No.: US11352611B2Publication Date: 2022-06-07
- Inventor: Jennifer L. Stamos , Alfred M. Lentzsch , Seung Kuk Park , Georg Mohr , Alan M. Lambowitz
- Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- International Application: PCT/US2018/054147 WO 20181003
- International Announcement: WO2019/070843 WO 20190411
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C30B29/58 ; G16B15/00 ; C30B7/00
Abstract:
A crystal structure of a Non-LTR-retroelement reverse transcriptase and methods of using the same to identify enzymes with improved activity are provided. Mutant reverse transcriptase enzymes and methods of using the same are also provided.
Public/Granted literature
- US20200255810A1 NON-LTR-RETROELEMENT REVERSE TRANSCRIPTASE AND USES THEREOF Public/Granted day:2020-08-13
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